Cholinergic autoantibodies in sinus-node dysfunction

Nine patients with sinus node disfunction were studied after a suggestion by doctors that the sinus node might be the target of an auto-immune response which leads to sinus node disfunction. Seven of the patients tested positive for autoantibodies, and the hypothesis regarding the auto-immune respon...

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Veröffentlicht in:	The Lancet (British edition) 1997-07, Vol.350 (9073), p.262-263
Hauptverfasser:	Ferrari, Inés, Levin, Mariano J, Elizari, Marcelo V, Rosenbaum, Mauricio B, Chiale, Pablo A
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Arrhythmia Agents - pharmacology Atropine - pharmacology Autoantibodies - pharmacology Biological and medical sciences Cardiac dysrhythmias Cardiology. Vascular system Heart Heart Rate - drug effects Humans Immune response Immunoglobulin G - pharmacology Medical research Medical sciences Nose Receptors, Cholinergic - drug effects Tachycardia, Sinus - immunology
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Beschreibung
Zusammenfassung:	Nine patients with sinus node disfunction were studied after a suggestion by doctors that the sinus node might be the target of an auto-immune response which leads to sinus node disfunction. Seven of the patients tested positive for autoantibodies, and the hypothesis regarding the auto-immune response is supported.
ISSN:	0140-6736 1474-547X
DOI:	10.1016/S0140-6736(05)62226-X