Verification and comparison of two different predictive equations in Hodgkin's disease
Divisione di Medicina Generale, Ospedale F. Del Ponte, Varese, Italy. BACKGROUND AND OBJECTIVE: In recent years, two predictive equations to estimate median expected survival at diagnosis for patients affected with Hodgkin's disease have been developed at the University of Pavia Medical School....
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Veröffentlicht in: | Haematologica (Roma) 1997-05, Vol.82 (3), p.324-327 |
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creator | Bettini, R Tonolini, M Maccianti, E |
description | Divisione di Medicina Generale, Ospedale F. Del Ponte, Varese, Italy.
BACKGROUND AND OBJECTIVE: In recent years, two predictive equations to estimate median expected survival at diagnosis for patients affected with Hodgkin's disease have been developed at the University of Pavia Medical School. The present retrospective work was aimed at testing correlation between mean survival estimated using the two equations and observed survival, and at comparing the results of the two different equations. METHODS: Fifty-three deceased patients were considered from a series of 114 consecutive ones. All these patients had been treated in a conventional way according to therapeutic modalities similar to those used in the series from which the two equations were derived. Expected median survival values calculated with the older, linear equation and with the newer exponential one were compared with observed survival. RESULTS: Mean survival of the whole series was over 24 years, with survival probabilities of 85% after 5 years and 74% after 10 years. Using the first predictive equation on the 53 deceased patients resulted in a satisfactory correlation between estimated median survival and real survival: Pearson's R correlation coefficient value is 0.5996, with a t value of 5.35 and p |
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BACKGROUND AND OBJECTIVE: In recent years, two predictive equations to estimate median expected survival at diagnosis for patients affected with Hodgkin's disease have been developed at the University of Pavia Medical School. The present retrospective work was aimed at testing correlation between mean survival estimated using the two equations and observed survival, and at comparing the results of the two different equations. METHODS: Fifty-three deceased patients were considered from a series of 114 consecutive ones. All these patients had been treated in a conventional way according to therapeutic modalities similar to those used in the series from which the two equations were derived. Expected median survival values calculated with the older, linear equation and with the newer exponential one were compared with observed survival. RESULTS: Mean survival of the whole series was over 24 years, with survival probabilities of 85% after 5 years and 74% after 10 years. Using the first predictive equation on the 53 deceased patients resulted in a satisfactory correlation between estimated median survival and real survival: Pearson's R correlation coefficient value is 0.5996, with a t value of 5.35 and p</description><identifier>ISSN: 0390-6078</identifier><identifier>EISSN: 1592-8721</identifier><identifier>PMID: 9234580</identifier><language>eng</language><publisher>Pavia: Haematologica</publisher><subject>Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Algorithms ; Biological and medical sciences ; Child ; Evaluation Studies as Topic ; Female ; Hematologic and hematopoietic diseases ; Hodgkin Disease - blood ; Hodgkin Disease - mortality ; Hodgkin Disease - pathology ; Humans ; Italy - epidemiology ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; Male ; Medical sciences ; Middle Aged ; Neoplasm Staging ; Prognosis ; Proportional Hazards Models ; Retrospective Studies ; Risk Factors ; Serum Albumin - analysis ; Sex Factors ; Survival Analysis</subject><ispartof>Haematologica (Roma), 1997-05, Vol.82 (3), p.324-327</ispartof><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2713993$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9234580$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bettini, R</creatorcontrib><creatorcontrib>Tonolini, M</creatorcontrib><creatorcontrib>Maccianti, E</creatorcontrib><title>Verification and comparison of two different predictive equations in Hodgkin's disease</title><title>Haematologica (Roma)</title><addtitle>Haematologica</addtitle><description>Divisione di Medicina Generale, Ospedale F. Del Ponte, Varese, Italy.
BACKGROUND AND OBJECTIVE: In recent years, two predictive equations to estimate median expected survival at diagnosis for patients affected with Hodgkin's disease have been developed at the University of Pavia Medical School. The present retrospective work was aimed at testing correlation between mean survival estimated using the two equations and observed survival, and at comparing the results of the two different equations. METHODS: Fifty-three deceased patients were considered from a series of 114 consecutive ones. All these patients had been treated in a conventional way according to therapeutic modalities similar to those used in the series from which the two equations were derived. Expected median survival values calculated with the older, linear equation and with the newer exponential one were compared with observed survival. RESULTS: Mean survival of the whole series was over 24 years, with survival probabilities of 85% after 5 years and 74% after 10 years. Using the first predictive equation on the 53 deceased patients resulted in a satisfactory correlation between estimated median survival and real survival: Pearson's R correlation coefficient value is 0.5996, with a t value of 5.35 and p</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Algorithms</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Evaluation Studies as Topic</subject><subject>Female</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Hodgkin Disease - blood</subject><subject>Hodgkin Disease - mortality</subject><subject>Hodgkin Disease - pathology</subject><subject>Humans</subject><subject>Italy - epidemiology</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neoplasm Staging</subject><subject>Prognosis</subject><subject>Proportional Hazards Models</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Serum Albumin - analysis</subject><subject>Sex Factors</subject><subject>Survival Analysis</subject><issn>0390-6078</issn><issn>1592-8721</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEtLxDAUhYMo4zj6E4QsfKwKadKkyVIGdYQBNzrbkiY3M9G-Jmkt_nuLFleXy_nOtzgnaJlyRROZ0_QULQlTJBEkl-foIsYPQihRKl-ghaIs45Is0W4HwTtvdO_bBuvGYtPWnQ4-Tm_rcD-22HrnIEDT4y6A9ab3X4DhOPx2IvYN3rR2_-mb-zixEXSES3TmdBXhar4r9P70-LbeJNvX55f1wzY5UMH7hNM0k6zMWWkNMwJomQrLBS8ZBUmpLFOgjqtUauYYCCGVIcxKk_NMS1ECW6G7P28X2uMAsS9qHw1UlW6gHWKRq2kOxuQEXs_gUNZgiy74WofvYh5iym_mXEejKxd0Y3z8x2ieMjWJVuj2Dzv4_WH0AYpY66qapLQYx1HSghWMZuwHR0J0zg</recordid><startdate>19970501</startdate><enddate>19970501</enddate><creator>Bettini, R</creator><creator>Tonolini, M</creator><creator>Maccianti, E</creator><general>Haematologica</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>19970501</creationdate><title>Verification and comparison of two different predictive equations in Hodgkin's disease</title><author>Bettini, R ; Tonolini, M ; Maccianti, E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h265t-521483b73bdc3c6e2b16d565b32e8228b1e2f5918a3f3e6689c03d8c754a86be3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Algorithms</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Evaluation Studies as Topic</topic><topic>Female</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Hodgkin Disease - blood</topic><topic>Hodgkin Disease - mortality</topic><topic>Hodgkin Disease - pathology</topic><topic>Humans</topic><topic>Italy - epidemiology</topic><topic>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neoplasm Staging</topic><topic>Prognosis</topic><topic>Proportional Hazards Models</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Serum Albumin - analysis</topic><topic>Sex Factors</topic><topic>Survival Analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bettini, R</creatorcontrib><creatorcontrib>Tonolini, M</creatorcontrib><creatorcontrib>Maccianti, E</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Haematologica (Roma)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bettini, R</au><au>Tonolini, M</au><au>Maccianti, E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Verification and comparison of two different predictive equations in Hodgkin's disease</atitle><jtitle>Haematologica (Roma)</jtitle><addtitle>Haematologica</addtitle><date>1997-05-01</date><risdate>1997</risdate><volume>82</volume><issue>3</issue><spage>324</spage><epage>327</epage><pages>324-327</pages><issn>0390-6078</issn><eissn>1592-8721</eissn><abstract>Divisione di Medicina Generale, Ospedale F. Del Ponte, Varese, Italy.
BACKGROUND AND OBJECTIVE: In recent years, two predictive equations to estimate median expected survival at diagnosis for patients affected with Hodgkin's disease have been developed at the University of Pavia Medical School. The present retrospective work was aimed at testing correlation between mean survival estimated using the two equations and observed survival, and at comparing the results of the two different equations. METHODS: Fifty-three deceased patients were considered from a series of 114 consecutive ones. All these patients had been treated in a conventional way according to therapeutic modalities similar to those used in the series from which the two equations were derived. Expected median survival values calculated with the older, linear equation and with the newer exponential one were compared with observed survival. RESULTS: Mean survival of the whole series was over 24 years, with survival probabilities of 85% after 5 years and 74% after 10 years. Using the first predictive equation on the 53 deceased patients resulted in a satisfactory correlation between estimated median survival and real survival: Pearson's R correlation coefficient value is 0.5996, with a t value of 5.35 and p</abstract><cop>Pavia</cop><pub>Haematologica</pub><pmid>9234580</pmid><tpages>4</tpages></addata></record> |
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subjects | Adolescent Adult Age Factors Aged Aged, 80 and over Algorithms Biological and medical sciences Child Evaluation Studies as Topic Female Hematologic and hematopoietic diseases Hodgkin Disease - blood Hodgkin Disease - mortality Hodgkin Disease - pathology Humans Italy - epidemiology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Middle Aged Neoplasm Staging Prognosis Proportional Hazards Models Retrospective Studies Risk Factors Serum Albumin - analysis Sex Factors Survival Analysis |
title | Verification and comparison of two different predictive equations in Hodgkin's disease |
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