Verification and comparison of two different predictive equations in Hodgkin's disease

Divisione di Medicina Generale, Ospedale F. Del Ponte, Varese, Italy. BACKGROUND AND OBJECTIVE: In recent years, two predictive equations to estimate median expected survival at diagnosis for patients affected with Hodgkin's disease have been developed at the University of Pavia Medical School....

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Veröffentlicht in:Haematologica (Roma) 1997-05, Vol.82 (3), p.324-327
Hauptverfasser: Bettini, R, Tonolini, M, Maccianti, E
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container_title Haematologica (Roma)
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creator Bettini, R
Tonolini, M
Maccianti, E
description Divisione di Medicina Generale, Ospedale F. Del Ponte, Varese, Italy. BACKGROUND AND OBJECTIVE: In recent years, two predictive equations to estimate median expected survival at diagnosis for patients affected with Hodgkin's disease have been developed at the University of Pavia Medical School. The present retrospective work was aimed at testing correlation between mean survival estimated using the two equations and observed survival, and at comparing the results of the two different equations. METHODS: Fifty-three deceased patients were considered from a series of 114 consecutive ones. All these patients had been treated in a conventional way according to therapeutic modalities similar to those used in the series from which the two equations were derived. Expected median survival values calculated with the older, linear equation and with the newer exponential one were compared with observed survival. RESULTS: Mean survival of the whole series was over 24 years, with survival probabilities of 85% after 5 years and 74% after 10 years. Using the first predictive equation on the 53 deceased patients resulted in a satisfactory correlation between estimated median survival and real survival: Pearson's R correlation coefficient value is 0.5996, with a t value of 5.35 and p
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Del Ponte, Varese, Italy. BACKGROUND AND OBJECTIVE: In recent years, two predictive equations to estimate median expected survival at diagnosis for patients affected with Hodgkin's disease have been developed at the University of Pavia Medical School. The present retrospective work was aimed at testing correlation between mean survival estimated using the two equations and observed survival, and at comparing the results of the two different equations. METHODS: Fifty-three deceased patients were considered from a series of 114 consecutive ones. All these patients had been treated in a conventional way according to therapeutic modalities similar to those used in the series from which the two equations were derived. Expected median survival values calculated with the older, linear equation and with the newer exponential one were compared with observed survival. 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Del Ponte, Varese, Italy. BACKGROUND AND OBJECTIVE: In recent years, two predictive equations to estimate median expected survival at diagnosis for patients affected with Hodgkin's disease have been developed at the University of Pavia Medical School. The present retrospective work was aimed at testing correlation between mean survival estimated using the two equations and observed survival, and at comparing the results of the two different equations. METHODS: Fifty-three deceased patients were considered from a series of 114 consecutive ones. All these patients had been treated in a conventional way according to therapeutic modalities similar to those used in the series from which the two equations were derived. Expected median survival values calculated with the older, linear equation and with the newer exponential one were compared with observed survival. 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source MEDLINE; DOAJ Directory of Open Access Journals
subjects Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Algorithms
Biological and medical sciences
Child
Evaluation Studies as Topic
Female
Hematologic and hematopoietic diseases
Hodgkin Disease - blood
Hodgkin Disease - mortality
Hodgkin Disease - pathology
Humans
Italy - epidemiology
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Male
Medical sciences
Middle Aged
Neoplasm Staging
Prognosis
Proportional Hazards Models
Retrospective Studies
Risk Factors
Serum Albumin - analysis
Sex Factors
Survival Analysis
title Verification and comparison of two different predictive equations in Hodgkin's disease
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