A rare case of de novo structural rearrangement of X chromosome diagnosed by amniocentesis

A dicentric X chromosome was found in a female fetus during cytogenetic studies performed on amniotic cells. Blood samples from the parents showed normal karyotypes and the pregnancy was terminated. The mechanism for the formation of this ‘de novo’ rearrangement is discussed.

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Bibliographische Detailangaben
Veröffentlicht in:	Prenatal diagnosis 1989-06, Vol.9 (6), p.443-445
Hauptverfasser:	Juan, J. L. Carrasco, Gómez, A. Otero, Mesa, M. C. Vilar, Miranda, J. L. García, Luque, J. M. Troyano, Ruiz, O. Morales, Hernández, J. Parache
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amniocentesis Biological and medical sciences Chromosome X De novo Dicentric Female Gynecology. Andrology. Obstetrics Humans Karyotyping Management. Prenatal diagnosis Medical sciences Pregnancy Pregnancy. Fetus. Placenta Prenatal diagnosis Sex Chromosome Aberrations - diagnosis X Chromosome - analysis
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Beschreibung
Zusammenfassung:	A dicentric X chromosome was found in a female fetus during cytogenetic studies performed on amniotic cells. Blood samples from the parents showed normal karyotypes and the pregnancy was terminated. The mechanism for the formation of this ‘de novo’ rearrangement is discussed.
ISSN:	0197-3851 1097-0223
DOI:	10.1002/pd.1970090611