A prospective randomized trial of interstitial radiofrequency therapy versus transurethral resection for the treatment of benign prostatic hyperplasia

Objective To carry out a prospective randomized trial comparing interstitial radiofrequency therapy (IRFT) with transurethral resection of the prostate (TURP) in the treatment of bladder outlet obstruction (BOO) caused by benign prostatic hyperplasia. Patients and methods The change in detrusor pressure at maximum flow (PdetQmax ) was chosen as the primary measure of outcome but the symptom score, Qmax and residual volume were also measured. Patients with urodynamic evidence of BOO were randomized to receive IRFT (n=25) or TURP (n=25); the urodynamics were repeated 6 months after treatment. Results There was a statistically significant reduction in PdetQmax at 6 months for TURP (P