Epidemiological and genetic observations on human schistosomiasis in Kinshasa, Zaire
A survey for Schistosoma intercalatum conducted in Kinshasa, Zaire, in September 1994 revealed a prevalence of 3·6% ( n = 167). Three isolates of schistosomes were made by exposing Bulinus wrighti to miracidia hatched from eggs collected from 2 infected children. Characterization of the isolates by...
Gespeichert in:
Veröffentlicht in: | Transactions of the Royal Society of Tropical Medicine and Hygiene 1997-05, Vol.91 (3), p.263-269 |
---|---|
Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | A survey for
Schistosoma intercalatum conducted in Kinshasa, Zaire, in September 1994 revealed a prevalence of 3·6% (
n = 167). Three isolates of schistosomes were made by exposing
Bulinus wrighti to miracidia hatched from eggs collected from 2 infected children. Characterization of the isolates by biochemical (isoenzymes of phosphoglucomutase), molecular (restriction fragment length polymorphism and randomly amplified polymorphic deoxyribonucleic acid analysis) and morphological (egg measurements) techniques confirmed the existence of an autochthonous transmission focus of
S. intercalatum in Kinshasa. The study also provided evidence of the occurrence of natural hybridization between
S. intercalatum and
S. haematobium. No potential snail host for either species was found in the 2 rivers examined. Apart from
Bu. globosus from Zambia and
Bu. wrighti, snail infection experiments showed an incompatible relationship between the parasite isolates and snails belonging to the
Bu. forskalii group, the
Bu. truncatus/Bu. tropicus complex, and the
Bu. africanus group. |
---|---|
ISSN: | 0035-9203 1878-3503 |
DOI: | 10.1016/S0035-9203(97)90068-7 |