Determinants of homologous blood usage utilizing autologous platelet-rich plasma in cardiac operations

The present study evaluated (1) the influence of the collection of autologous platelet-rich plasma intraoperatively in addition to intraoperative autotransfusion on homologous blood usage and bleeding in cardiac operations; (2) the influence of age, sex, body surface area, type of operation, and reo...

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Veröffentlicht in:The Annals of thoracic surgery 1989-06, Vol.47 (6), p.897-902
Hauptverfasser: Giordano, Gerald F., Rivers, Shirley L., Chung, George K.T., Mammana, Robert B., Marco, Joseph D., Raczkowski, Allen R., Sabbagh, Adib, Sanderson, Richard G., Strug, Burt S.
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Sprache:eng
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Zusammenfassung:The present study evaluated (1) the influence of the collection of autologous platelet-rich plasma intraoperatively in addition to intraoperative autotransfusion on homologous blood usage and bleeding in cardiac operations; (2) the influence of age, sex, body surface area, type of operation, and reoperations on homologous blood usage and bleeding in cardiac operations utilizing intraoperative autotransfusion and autologous platelet-rich plasma collected intraoperatively; and (3) the influence of the preoperative administration of aspirin, Persantine (dipyridamole), heparin sodium, thrombolytic agents, Coumadin (crystalline warfarin sodium), and nonsteroid, antiinflammatory drugs on homologous blood usage and bleeding in cardiac operations utilizing intraoperative autotransfusion and autologous platelet-rich plasma collected intraoperatively. The results demonstrated a decrease in homologous blood use and bleeding when autologous platet-rich plasma is collected in addition to the use of intraoperative autotransfusion. All of the patient and procedural variables influenced homologous blood usage and bleeding to some extent. Only the thrombolytic agents affected blond usage by increasing homologous plasma usage. All other drugs evaluated did not influence blood utilization or the amount of bleeding intraoperatively or postoperatively.
ISSN:0003-4975
1552-6259
DOI:10.1016/0003-4975(89)90031-3