Role of Adenosine in the Cardiac Catheterization Laboratory

After the vasodilating reserve capacity of R2 is exhausted, (R1) becomes flow limiting (Fig. 2). [...]coronary flow reserve ratio is a useful functional measure of stenosis severity and is the basis by which vasodilator perfusion testing can detect critical coronary stenosis. The data (Fig. 4) show a poor correlation between angiographic percent diameter stenosis and translesional gradient, whereas the ratio of proximal-to-distal total velocity integral correlated strongly with the translesional pressure gradient (r = 0.8, p 1.7:1 is consistent with critical epicardial stenosis and provides on-line assessment for intervention.