Effects of dietary manipulations and glucose infusion on glucagon response during exercise in rats

Maurice Tadjoré, Raynald Bergeron, Martin Latour, François Désy, Claude Warren, and Jean-Marc Lavoie Département d'Éducation Physique, Université de Montréal, Montreal, Quebec, Canada H3C 3J7 Received 31 December 1996; accepted in final form 17 March 1997. Tadjoré, Maurice, Raynald Bergeron, Martin Latour, François Désy, Claude Warren, and Jean-Marc Lavoie. Effects of dietary manipulations and glucose infusion on glucagon response during exercise in rats. J. Appl. Physiol. 83(1): 148-152, 1997. The purpose of the present investigation was to test the hypothesis that blood glucose concentration is not always related to glucagon response during exercise. Three groups of rats were submitted to a prolonged (3-h) swimming exercise. Two groups of rats had their normal food intake restricted by 50% the night before the experiment. One of these two groups of rats was intravenously infused with glucose throughout exercise to maintain euglycemia. The third group of rats swam while under normal dietary conditions. Plasma glucose, sampled in arterial blood, was reduced ( P