Wegener granulomatosis: Prostatic involvement and bladder outlet obstruction

Renal involvement is present in about 90 percent of patients with Wegener granulomatosis and only sporadically is the remainder of the genitourinary tract affected. Prior to 1974, the mean survival rate was five months from the time of diagnosis. Since 1974, therapy with cytotoxic drugs, cyclophosph...

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Veröffentlicht in:Urology (Ridgewood, N.J.) N.J.), 1989-07, Vol.34 (1), p.43-45
Hauptverfasser: Vaught, Winston W., Wilson, Torrence M., Raife, Michael J., Horne, Daniel W.
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container_title Urology (Ridgewood, N.J.)
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creator Vaught, Winston W.
Wilson, Torrence M.
Raife, Michael J.
Horne, Daniel W.
description Renal involvement is present in about 90 percent of patients with Wegener granulomatosis and only sporadically is the remainder of the genitourinary tract affected. Prior to 1974, the mean survival rate was five months from the time of diagnosis. Since 1974, therapy with cytotoxic drugs, cyclophosphamide or azathioprine, has produced remissions in about 95 percent of patients. Herein, a case is reported that presented with bladder outlet obstructive symptoms, secondary to prostatic involvement with Wegener granulomatosis. After treatment with cyclophospharnide and prednisone, the patient's urinary obstructive symptoms promptly resolved.
doi_str_mv 10.1016/0090-4295(89)90155-6
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subjects Biological and medical sciences
Granulomatosis with Polyangiitis - complications
Humans
Male
Medical sciences
Middle Aged
Necrosis
Prostate - pathology
Prostatitis - complications
Prostatitis - pathology
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Urinary Bladder Neck Obstruction - etiology
title Wegener granulomatosis: Prostatic involvement and bladder outlet obstruction
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