Wegener granulomatosis: Prostatic involvement and bladder outlet obstruction
Renal involvement is present in about 90 percent of patients with Wegener granulomatosis and only sporadically is the remainder of the genitourinary tract affected. Prior to 1974, the mean survival rate was five months from the time of diagnosis. Since 1974, therapy with cytotoxic drugs, cyclophosph...
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Veröffentlicht in: | Urology (Ridgewood, N.J.) N.J.), 1989-07, Vol.34 (1), p.43-45 |
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creator | Vaught, Winston W. Wilson, Torrence M. Raife, Michael J. Horne, Daniel W. |
description | Renal involvement is present in about 90 percent of patients with Wegener granulomatosis and only sporadically is the remainder of the genitourinary tract affected. Prior to 1974, the mean survival rate was five months from the time of diagnosis. Since 1974, therapy with cytotoxic drugs, cyclophosphamide or azathioprine, has produced remissions in about 95 percent of patients. Herein, a case is reported that presented with bladder outlet obstructive symptoms, secondary to prostatic involvement with Wegener granulomatosis. After treatment with cyclophospharnide and prednisone, the patient's urinary obstructive symptoms promptly resolved. |
doi_str_mv | 10.1016/0090-4295(89)90155-6 |
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Prior to 1974, the mean survival rate was five months from the time of diagnosis. Since 1974, therapy with cytotoxic drugs, cyclophosphamide or azathioprine, has produced remissions in about 95 percent of patients. Herein, a case is reported that presented with bladder outlet obstructive symptoms, secondary to prostatic involvement with Wegener granulomatosis. After treatment with cyclophospharnide and prednisone, the patient's urinary obstructive symptoms promptly resolved.</description><identifier>ISSN: 0090-4295</identifier><identifier>EISSN: 1527-9995</identifier><identifier>DOI: 10.1016/0090-4295(89)90155-6</identifier><identifier>PMID: 2749956</identifier><identifier>CODEN: URGYAZ</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Biological and medical sciences ; Granulomatosis with Polyangiitis - complications ; Humans ; Male ; Medical sciences ; Middle Aged ; Necrosis ; Prostate - pathology ; Prostatitis - complications ; Prostatitis - pathology ; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. 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Prior to 1974, the mean survival rate was five months from the time of diagnosis. Since 1974, therapy with cytotoxic drugs, cyclophosphamide or azathioprine, has produced remissions in about 95 percent of patients. Herein, a case is reported that presented with bladder outlet obstructive symptoms, secondary to prostatic involvement with Wegener granulomatosis. After treatment with cyclophospharnide and prednisone, the patient's urinary obstructive symptoms promptly resolved.</description><subject>Biological and medical sciences</subject><subject>Granulomatosis with Polyangiitis - complications</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Necrosis</subject><subject>Prostate - pathology</subject><subject>Prostatitis - complications</subject><subject>Prostatitis - pathology</subject><subject>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</subject><subject>Urinary Bladder Neck Obstruction - etiology</subject><issn>0090-4295</issn><issn>1527-9995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMFu1DAQhi1UtGwLbwBSLkX0ELCd2I57QEKrFpBWoodWHK2JPamMkrjYzkq8fb3sarlxmsN8_6-Zj5C3jH5klMlPlGpat1yLD52-0pQJUcsXZM0EV7XWWpyR9Ql5Rc5T-kUplVKqFVlx1RZCrsn2Jz7ijLF6jDAvY5ggh-TTdXUXQ8qQva38vAvjDieccwWzq_oRnCuJsOQRcxX6lONisw_za_JygDHhm-O8IA-3N_ebb_X2x9fvmy_b2jadyrVmbUspAwnSKSbbHsAJKhXIvmm4bfhAOwcd0yhay4XtmVAg-qFxBWiVbC7I-0PvUwy_F0zZTD5ZHEeYMSzJKM0Yl1IUsD2AtnyTIg7mKfoJ4h_DqNlLNHtDZm_IdNr8lWj2_e-O_Us_oTuFjtbK_vK4h2RhHIo669O_bi255EwV7vOBwyJj5zGaZD3OFp2PaLNxwf__kGdzFY5A</recordid><startdate>19890701</startdate><enddate>19890701</enddate><creator>Vaught, Winston W.</creator><creator>Wilson, Torrence M.</creator><creator>Raife, Michael J.</creator><creator>Horne, Daniel W.</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19890701</creationdate><title>Wegener granulomatosis: Prostatic involvement and bladder outlet obstruction</title><author>Vaught, Winston W. ; Wilson, Torrence M. ; Raife, Michael J. ; Horne, Daniel W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c387t-9144001a6a6d7164baad5067a6b332c32f08da819e54c25cb157a5bf3d6b34763</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Biological and medical sciences</topic><topic>Granulomatosis with Polyangiitis - complications</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Necrosis</topic><topic>Prostate - pathology</topic><topic>Prostatitis - complications</topic><topic>Prostatitis - pathology</topic><topic>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</topic><topic>Urinary Bladder Neck Obstruction - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vaught, Winston W.</creatorcontrib><creatorcontrib>Wilson, Torrence M.</creatorcontrib><creatorcontrib>Raife, Michael J.</creatorcontrib><creatorcontrib>Horne, Daniel W.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Urology (Ridgewood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vaught, Winston W.</au><au>Wilson, Torrence M.</au><au>Raife, Michael J.</au><au>Horne, Daniel W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Wegener granulomatosis: Prostatic involvement and bladder outlet obstruction</atitle><jtitle>Urology (Ridgewood, N.J.)</jtitle><addtitle>Urology</addtitle><date>1989-07-01</date><risdate>1989</risdate><volume>34</volume><issue>1</issue><spage>43</spage><epage>45</epage><pages>43-45</pages><issn>0090-4295</issn><eissn>1527-9995</eissn><coden>URGYAZ</coden><abstract>Renal involvement is present in about 90 percent of patients with Wegener granulomatosis and only sporadically is the remainder of the genitourinary tract affected. Prior to 1974, the mean survival rate was five months from the time of diagnosis. Since 1974, therapy with cytotoxic drugs, cyclophosphamide or azathioprine, has produced remissions in about 95 percent of patients. Herein, a case is reported that presented with bladder outlet obstructive symptoms, secondary to prostatic involvement with Wegener granulomatosis. After treatment with cyclophospharnide and prednisone, the patient's urinary obstructive symptoms promptly resolved.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>2749956</pmid><doi>10.1016/0090-4295(89)90155-6</doi><tpages>3</tpages></addata></record> |
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source | MEDLINE; Elsevier ScienceDirect Journals Complete |
subjects | Biological and medical sciences Granulomatosis with Polyangiitis - complications Humans Male Medical sciences Middle Aged Necrosis Prostate - pathology Prostatitis - complications Prostatitis - pathology Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Urinary Bladder Neck Obstruction - etiology |
title | Wegener granulomatosis: Prostatic involvement and bladder outlet obstruction |
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