Circadian rhythms in mouse suprachiasmatic nucleus explants on multimicroelectrode plates

Circadian rhythms in mouse suprachiasmatic nucleus explants on multimicroelectrode plates

The suprachiasmatic nucleus (SCN) of the mammalian hypothalamus functions as a circadian pacemaker. This study used multimicroelectrode plates to measure extracellular action potential activity simultaneously from multiple sites within the cultured mouse SCN. Neurons within the isolated mouse SCN ex...

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Veröffentlicht in:Brain research 1997-05, Vol.757 (2), p.285-290
Hauptverfasser: Herzog, Erik D, Geusz, Michael E, Khalsa, Sat Bir S, Straume, Martin, Block, Gene D
Format: Artikel
Sprache:eng
Schlagworte:
Action Potentials
Animals
Cells, Cultured
Circadian Rhythm
Electrophysiology
Extracellular Space - physiology
Mice
Mice, Inbred C57BL
Microelectrodes
Neurons - physiology
Pacemaker
Planar electrode array
Suprachiasmatic nucleus
Suprachiasmatic Nucleus - cytology
Suprachiasmatic Nucleus - physiology
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Zusammenfassung:The suprachiasmatic nucleus (SCN) of the mammalian hypothalamus functions as a circadian pacemaker. This study used multimicroelectrode plates to measure extracellular action potential activity simultaneously from multiple sites within the cultured mouse SCN. Neurons within the isolated mouse SCN expressed a circadian rhythm in spontaneous firing rate for weeks in culture.
ISSN:0006-8993
1872-6240
DOI:10.1016/S0006-8993(97)00337-5