Stability constants and 1H relaxation effects of ternary complexes formed between gd-dtpa, gd-dtpa-bma, gd-dota, and gd-edta and citrate, phosphate, and carbonate ions

Formation of ternary complexes between Gd‐DTPA, Gd‐DTPA‐BMA, and Gd‐DOTA, used as contrast enhancement agents in MRI and the endogenously available carbonate and phosphate ions, has been demonstrated. The extent of ternary complex formation and its effect on the proton relaxation, measured at 9 MHz,...

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Veröffentlicht in:Magnetic resonance in medicine 1997-07, Vol.38 (1), p.146-150
Hauptverfasser: Burai, László, Hietapelto, Vesa, Király, RóBert, Tóth, éva, Brücher, Ernő
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Sprache:eng
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Zusammenfassung:Formation of ternary complexes between Gd‐DTPA, Gd‐DTPA‐BMA, and Gd‐DOTA, used as contrast enhancement agents in MRI and the endogenously available carbonate and phosphate ions, has been demonstrated. The extent of ternary complex formation and its effect on the proton relaxation, measured at 9 MHz, rates is negligible at around pH
ISSN:0740-3194
1522-2594
DOI:10.1002/mrm.1910380120