DNA ploidy and pS2 protein expression in breast cancer

The DNA content of ductal breast carcinomas of varying histological grade was measured using static image cytometry and correlated with pS2 expression in the tumour cells. Our study was performed on imprint of surgical biopsies of 60 women with ductal breast cancer. A statistically significant diffe...

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Veröffentlicht in:	Cytopathology (Oxford) 1997-06, Vol.8 (3), p.171-176
Hauptverfasser:	IOAKIM-LIOSSI, A., KARAKITSOS, P., ARONI, K., MARKOPOULOS, C., DELIVELIOTI, K., GOGAS, J., KYRKOU, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aneuploidy Breast - chemistry Breast - pathology breast cancer Breast Neoplasms - chemistry Breast Neoplasms - genetics Breast Neoplasms - pathology Carcinoma, Ductal, Breast - chemistry Carcinoma, Ductal, Breast - genetics Carcinoma, Ductal, Breast - pathology DNA ploidy DNA, Neoplasm - analysis DNA, Neoplasm - genetics Female Gene Expression Regulation, Neoplastic Humans Image Cytometry Immunohistochemistry Ploidies Prospective Studies Proteins - analysis Proteins - genetics pS2 protein Trefoil Factor-1 Tumor Suppressor Proteins
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Zusammenfassung:	The DNA content of ductal breast carcinomas of varying histological grade was measured using static image cytometry and correlated with pS2 expression in the tumour cells. Our study was performed on imprint of surgical biopsies of 60 women with ductal breast cancer. A statistically significant difference was observed between pS2+ expression and grade of malignancy (P
ISSN:	0956-5507 1365-2303
DOI:	10.1046/j.1365-2303.1997.44175441.x