Gap junctions: Getting the message through

Gap junctions: Getting the message through

Connexin proteins make intercellular channels –  gap junctions –  which provide a direct pathway for cell–cell signaling in vertebrates. Studies of mice lacking connexin genes have demonstrated the need for intercellular transfer of messenger molecules and are uncovering the specific functions of ea...

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Veröffentlicht in:Current biology 1997-06, Vol.7 (6), p.R340-R344
Hauptverfasser: Nicholson, Simone M., Bruzzone, Roberto
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Cell Communication - physiology
Connexins - physiology
Female
Gap Junctions - physiology
Mice
Mice, Knockout
Oogenesis - physiology
Ovulation - physiology
Transgenes
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Zusammenfassung:Connexin proteins make intercellular channels –  gap junctions –  which provide a direct pathway for cell–cell signaling in vertebrates. Studies of mice lacking connexin genes have demonstrated the need for intercellular transfer of messenger molecules and are uncovering the specific functions of each connexin.
ISSN:0960-9822
1879-0445
DOI:10.1016/S0960-9822(06)00169-2