High prevalence of GB virus-C/hepatitis G virus infection in liver transplant recipients

To determine the prevalence of GB virus-C/hepatitis G virus (GBV-C/HGV) infection in liver transplant recipients transplanted for non-hepatitis C virus indications, 44 patients transplanted for cryptogenic, autoimmune, hepatitis B, or cholestatic liver disease and 91 non-liver transplantation (LT) p...

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Veröffentlicht in:	Transplantation 1997-06, Vol.63 (11), p.1695-1697
Hauptverfasser:	DICKSON, R. C, QIAN, K, LAU, J. Y. N
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alanine Transaminase - blood Biological and medical sciences Biopsy Female Flaviviridae - genetics Hepatitis, Viral, Human - blood Hepatitis, Viral, Human - epidemiology Humans Liver - pathology Liver Transplantation - pathology Liver Transplantation - statistics & numerical data Liver, biliary tract, pancreas, portal circulation, spleen Longitudinal Studies Male Medical sciences Middle Aged Prevalence Prospective Studies RNA, Messenger - blood Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the digestive system
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Zusammenfassung:	To determine the prevalence of GB virus-C/hepatitis G virus (GBV-C/HGV) infection in liver transplant recipients transplanted for non-hepatitis C virus indications, 44 patients transplanted for cryptogenic, autoimmune, hepatitis B, or cholestatic liver disease and 91 non-liver transplantation (LT) patients with similar diagnoses seen in the same study period (control group) were studied. HGV RNA was detected by reverse transcription polymerase chain reaction with primers from the 5'-untranslated region. GBV-C/HGV RNA was commonly detected in post-LT patients compared with the control group (28/44 [64%] vs. 13/91 [14%]; P
ISSN:	0041-1337 1534-6080
DOI:	10.1097/00007890-199706150-00028