Resting energy expenditure is increased in infants and children with extrahepatic biliary atresia

Resting energy expenditure is increased in infants and children with extrahepatic biliary atresia

To determine if liver dysfunction in children affects energy and macronutrient homeostasis, we performed 13 metabolic studies in 11 patients (age, 17.8±5.9 months [mean±SEM]) with extrahepatic biliary atresia (EHBA). Nutritional balance, indirect calorimetry, anthropometry, and biochemical liver fun...

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Veröffentlicht in:Journal of pediatric surgery 1989-06, Vol.24 (6), p.534-538
Hauptverfasser: Pierro, Agostino, Koletzko, Bert, Carnielli, Virgilio, Superina, Riccardo A., Roberts, Eva A., Filler, Robert M., Smith, John, Heim, Tibor
Format: Artikel
Sprache:eng
Schlagworte:
Basal Metabolism
Biliary Atresia - diagnosis
Biliary Atresia - metabolism
Body Height
Body Weight
Calorimetry - methods
Carbohydrate Metabolism
Child
Child, Preschool
Energy Metabolism
Extrahepatic biliary atresia
Female
Humans
Infant
Liver - physiopathology
Male
Nutrition Disorders - etiology
Nutritional Status
Oxygen Consumption
substrate utilisation
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Zusammenfassung:To determine if liver dysfunction in children affects energy and macronutrient homeostasis, we performed 13 metabolic studies in 11 patients (age, 17.8±5.9 months [mean±SEM]) with extrahepatic biliary atresia (EHBA). Nutritional balance, indirect calorimetry, anthropometry, and biochemical liver function tests were utilised. Sixtyfour percent of the energy losses were in the form of stool fat. Energy expenditure (68 kcal/kd/d) was 29% higher than normal ( P
ISSN:0022-3468
1531-5037
DOI:10.1016/S0022-3468(89)80500-7