Tolerance of class I histocompatibility antigens expressed extrathymically

ALTHOUGH convincing evidence has been obtained for the imposition of self-tolerance by the intrathymic deletion of self-reactive T cells 1–4 , the development of tolerance to antigens which are expressed only in the periphery is not so well understood. We have approached this question by creating tr...

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Veröffentlicht in:Nature (London) 1989-06, Vol.339 (6226), p.622-624
Hauptverfasser: Morahan, Grant, Allison, Janette, Miller, J. F. A. P
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Sprache:eng
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