Variable expression of P fimbriae in Escherichia coli urinary tract infection

Fresh urinary isolates were examined by immunofluorescence with polyclonal rabbit antibodies against type 1 and P fimbriae. This procedure showed P-fimbriate Escherichia coli in 22 of 24 samples from patients with asymptomatic bacteriuria, 24 of 26 samples from patients with cystitis, and 6 of 6 sam...

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Veröffentlicht in:The Lancet (British edition) 1989-06, Vol.1 (8652), p.1414-1418
Hauptverfasser: LICHODZIEJEWSKA, M, TOPLEY, N, STEADMAN, R, MACKENZIE, R. K, JONES, K. V, WILLIAMS, J. D
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Sprache:eng
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Zusammenfassung:Fresh urinary isolates were examined by immunofluorescence with polyclonal rabbit antibodies against type 1 and P fimbriae. This procedure showed P-fimbriate Escherichia coli in 22 of 24 samples from patients with asymptomatic bacteriuria, 24 of 26 samples from patients with cystitis, and 6 of 6 samples from patients with pyelonephritis. Type 1 fimbriae were expressed by less than 40% of isolates in all three groups. There was no relation between the presence of symptoms or the site of infection and fimbrial expression, of P or type 1, by bacteria adherent to freshly isolated uroepithelial cells.
ISSN:0140-6736
1474-547X