Linkage analysis of seven kindreds with the X-linked lymphoproliferative syndrome (XLP) confirms that the XLP locus is near DXS42 and DXS37

Analysis of seven kindreds indicates that the XLP locus exhibits 1% recombination with DXS42 (lod = 17.5) and no recombination with DXS37 (lod = 13.3).

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Bibliographische Detailangaben
Veröffentlicht in:	Human genetics 1989-07, Vol.82 (4), p.354-358
Hauptverfasser:	SKARE, J. C, GRIERSON, H. L, SULLIVAN, J. L, NUSSBAUM, R. L, PURTILO, D. T, SYLLA, B. S, LENOIR, G. M, REILLY, D. S, WHITE, B. N, MILUNSKY, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chromosome Mapping Female Genetic Linkage Genetic Markers Hematologic and hematopoietic diseases Humans Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoproliferative Disorders - genetics Male Medical sciences Pedigree Polymorphism, Restriction Fragment Length Recombination, Genetic Syndrome X Chromosome
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Beschreibung
Zusammenfassung:	Analysis of seven kindreds indicates that the XLP locus exhibits 1% recombination with DXS42 (lod = 17.5) and no recombination with DXS37 (lod = 13.3).
ISSN:	0340-6717 1432-1203
DOI:	10.1007/BF00273997