Antifungal Diterpenoid Alkaloids from Delphinium denudatum
The roots of Delphinium denudatum have yielded a new diterpenoid alkaloid, 8-acetylheterophyllisine (1), in addition to the known alkaloids vilmorrianone (2), panicutine (3), denudatine (4), isotalatizidine (5), and condelphine (6), as well as 3-hydroxy-2-methyl-4H-pyran-4-one (7). Compounds 1, 3, a...
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Veröffentlicht in: | Journal of natural products (Washington, D.C.) D.C.), 1997-05, Vol.60 (5), p.472-474 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | The roots of Delphinium denudatum have yielded a new diterpenoid alkaloid, 8-acetylheterophyllisine (1), in addition to the known alkaloids vilmorrianone (2), panicutine (3), denudatine (4), isotalatizidine (5), and condelphine (6), as well as 3-hydroxy-2-methyl-4H-pyran-4-one (7). Compounds 1, 3, and 7 have not been isolated from this plant previously. The structures of compounds 1, 3, and 7 were determined through spectral and X-ray diffraction analyses. Compounds 1−3 have shown antifungal activity against a number of human pathogenic fungi. |
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ISSN: | 0163-3864 1520-6025 |
DOI: | 10.1021/np960663n |