Mammography of breast carcinoma in women who have mutations of the breast cancer gene BRCA1: initial experience

We describe for the first time (to our knowledge) the mammographic appearance of breast cancer and breast density in carriers of the breast cancer gene BRCA1. The mammographic appearance of breast cancer in BRCA1 carriers was similar to that in the general population. All mammographic densities were...

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Veröffentlicht in:	American journal of roentgenology (1976) 1997-06, Vol.168 (6), p.1599-1602
Hauptverfasser:	Helvie, MA, Roubidoux, MA, Weber, BL, Merajver, SD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Breast Neoplasms - diagnostic imaging Breast Neoplasms - genetics Carcinoma in Situ - diagnostic imaging Carcinoma in Situ - genetics Carcinoma, Ductal, Breast - diagnostic imaging Carcinoma, Ductal, Breast - genetics Female Genes, BRCA1 - genetics Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Mammography Medical sciences Middle Aged Mutation Risk Factors Tumors
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Beschreibung
Zusammenfassung:	We describe for the first time (to our knowledge) the mammographic appearance of breast cancer and breast density in carriers of the breast cancer gene BRCA1. The mammographic appearance of breast cancer in BRCA1 carriers was similar to that in the general population. All mammographic densities were observed. Appropriate mammographic management of these extremely high-risk patients is yet to be determined.
ISSN:	0361-803X 1546-3141
DOI:	10.2214/ajr.168.6.9168735