Regression of uterine low-grade smooth-muscle tumors metastatic to the lung after oophorectomy
Background: Metastatic uterine low-grade smooth-muscle tumors may present with pulmonary symptoms and radiographic lung abnormalities consistent with metastatic neoplasms. Ovarian hormone stimulation of these smoothmuscle tumors has been suggested, but the role of surgical or medical oophorectomy ha...
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Veröffentlicht in: | Obstetrics and gynecology (New York. 1953) 1997-05, Vol.89 (5), p.850-852 |
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container_title | Obstetrics and gynecology (New York. 1953) |
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creator | Abu-Rustum, Nadeem R. Curtin, John P. Burt, Michael Jones, Walter B. |
description | Background: Metastatic uterine low-grade smooth-muscle tumors may present with pulmonary symptoms and radiographic lung abnormalities consistent with metastatic neoplasms. Ovarian hormone stimulation of these smoothmuscle tumors has been suggested, but the role of surgical or medical oophorectomy has not been established in patients with metastatic disease.
Cases: Two women with histologically confirmed uterine low-grade smooth-muscle tumors metastatic to the lung had progressive and complete tumor regression after oophorectomy and no further therapy.
Conclusion: Some uterine low-grade smooth-muscle tumors metastatic to the lung regress after oophorectomy. Removing ovarian hormone stimulation may result in complete tumor regression without the need for further therapy. |
doi_str_mv | 10.1016/S0029-7844(97)00033-1 |
format | Article |
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Cases: Two women with histologically confirmed uterine low-grade smooth-muscle tumors metastatic to the lung had progressive and complete tumor regression after oophorectomy and no further therapy.
Conclusion: Some uterine low-grade smooth-muscle tumors metastatic to the lung regress after oophorectomy. Removing ovarian hormone stimulation may result in complete tumor regression without the need for further therapy.</description><identifier>ISSN: 0029-7844</identifier><identifier>EISSN: 1873-233X</identifier><identifier>DOI: 10.1016/S0029-7844(97)00033-1</identifier><identifier>PMID: 9166348</identifier><identifier>CODEN: OBGNAS</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Biological and medical sciences ; Diagnosis, Differential ; Disease-Free Survival ; Female ; Female genital diseases ; Follow-Up Studies ; Gynecology. Andrology. Obstetrics ; Humans ; Leiomyoma - diagnostic imaging ; Leiomyoma - surgery ; Leiomyosarcoma - diagnostic imaging ; Leiomyosarcoma - secondary ; Leiomyosarcoma - surgery ; Lung Neoplasms - diagnostic imaging ; Lung Neoplasms - secondary ; Lung Neoplasms - surgery ; Medical sciences ; Ovariectomy ; Radiography ; Remission Induction ; Tumors ; Uterine Neoplasms - pathology</subject><ispartof>Obstetrics and gynecology (New York. 1953), 1997-05, Vol.89 (5), p.850-852</ispartof><rights>1997 The American College of Obstetricians and Gynecologists</rights><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5004-6bebbbe286dc4cfa667cb4b0430b11eeaa57d2694390ac4658bf8c1629c46c4e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2650490$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9166348$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Abu-Rustum, Nadeem R.</creatorcontrib><creatorcontrib>Curtin, John P.</creatorcontrib><creatorcontrib>Burt, Michael</creatorcontrib><creatorcontrib>Jones, Walter B.</creatorcontrib><title>Regression of uterine low-grade smooth-muscle tumors metastatic to the lung after oophorectomy</title><title>Obstetrics and gynecology (New York. 1953)</title><addtitle>Obstet Gynecol</addtitle><description>Background: Metastatic uterine low-grade smooth-muscle tumors may present with pulmonary symptoms and radiographic lung abnormalities consistent with metastatic neoplasms. Ovarian hormone stimulation of these smoothmuscle tumors has been suggested, but the role of surgical or medical oophorectomy has not been established in patients with metastatic disease.
Cases: Two women with histologically confirmed uterine low-grade smooth-muscle tumors metastatic to the lung had progressive and complete tumor regression after oophorectomy and no further therapy.
Conclusion: Some uterine low-grade smooth-muscle tumors metastatic to the lung regress after oophorectomy. Removing ovarian hormone stimulation may result in complete tumor regression without the need for further therapy.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Diagnosis, Differential</subject><subject>Disease-Free Survival</subject><subject>Female</subject><subject>Female genital diseases</subject><subject>Follow-Up Studies</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Leiomyoma - diagnostic imaging</subject><subject>Leiomyoma - surgery</subject><subject>Leiomyosarcoma - diagnostic imaging</subject><subject>Leiomyosarcoma - secondary</subject><subject>Leiomyosarcoma - surgery</subject><subject>Lung Neoplasms - diagnostic imaging</subject><subject>Lung Neoplasms - secondary</subject><subject>Lung Neoplasms - surgery</subject><subject>Medical sciences</subject><subject>Ovariectomy</subject><subject>Radiography</subject><subject>Remission Induction</subject><subject>Tumors</subject><subject>Uterine Neoplasms - pathology</subject><issn>0029-7844</issn><issn>1873-233X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkF2L1DAUQIMo67j6ExbyIKIP0ZsmTZsnkcUvWBD8AJ8MaXo7jbbNbJI67L83szPMq08hyTm54RByxeE1B67efAOoNGtaKV_q5hUACMH4A7LhbSNYJcTPh2RzRh6TJyn9LhBXWlyQC82VErLdkF9fcRsxJR8WGga6Zox-QTqFPdtG2yNNcwh5ZPOa3IQ0r3OIic6Ybco2e0dzoHkswrpsqR2KTkPYjSGiy2G-e0oeDXZK-Oy0XpIfH95_v_7Ebr58_Hz97oa5GkAy1WHXdVi1qnfSDVapxnWyAymg4xzR2rrpK6Wl0GCdVHXbDa3jqtJl4ySKS_Li-O4uhtsVUzazTw6nyS4Y1mQaDVzWqilgfQRdDClFHMwu-tnGO8PBHLqa-67mEM3oxtx3Nbx4V6cBazdjf7ZOIcv989O9Tc5OQ7SL8-mMVaoGqaFg8ojtw1RapT_TusdoRrRTHg_DQFU1MK51A6UMZ-WkkkV7e9SwNPzri5Gcx8Vh7w-hTR_8f_7_D1JjpdQ</recordid><startdate>199705</startdate><enddate>199705</enddate><creator>Abu-Rustum, Nadeem R.</creator><creator>Curtin, John P.</creator><creator>Burt, Michael</creator><creator>Jones, Walter B.</creator><general>Elsevier Inc</general><general>The American College of Obstetricians and Gynecologists</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199705</creationdate><title>Regression of uterine low-grade smooth-muscle tumors metastatic to the lung after oophorectomy</title><author>Abu-Rustum, Nadeem R. ; Curtin, John P. ; Burt, Michael ; Jones, Walter B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5004-6bebbbe286dc4cfa667cb4b0430b11eeaa57d2694390ac4658bf8c1629c46c4e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Diagnosis, Differential</topic><topic>Disease-Free Survival</topic><topic>Female</topic><topic>Female genital diseases</topic><topic>Follow-Up Studies</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Leiomyoma - diagnostic imaging</topic><topic>Leiomyoma - surgery</topic><topic>Leiomyosarcoma - diagnostic imaging</topic><topic>Leiomyosarcoma - secondary</topic><topic>Leiomyosarcoma - surgery</topic><topic>Lung Neoplasms - diagnostic imaging</topic><topic>Lung Neoplasms - secondary</topic><topic>Lung Neoplasms - surgery</topic><topic>Medical sciences</topic><topic>Ovariectomy</topic><topic>Radiography</topic><topic>Remission Induction</topic><topic>Tumors</topic><topic>Uterine Neoplasms - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Abu-Rustum, Nadeem R.</creatorcontrib><creatorcontrib>Curtin, John P.</creatorcontrib><creatorcontrib>Burt, Michael</creatorcontrib><creatorcontrib>Jones, Walter B.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Abu-Rustum, Nadeem R.</au><au>Curtin, John P.</au><au>Burt, Michael</au><au>Jones, Walter B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Regression of uterine low-grade smooth-muscle tumors metastatic to the lung after oophorectomy</atitle><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle><addtitle>Obstet Gynecol</addtitle><date>1997-05</date><risdate>1997</risdate><volume>89</volume><issue>5</issue><spage>850</spage><epage>852</epage><pages>850-852</pages><issn>0029-7844</issn><eissn>1873-233X</eissn><coden>OBGNAS</coden><abstract>Background: Metastatic uterine low-grade smooth-muscle tumors may present with pulmonary symptoms and radiographic lung abnormalities consistent with metastatic neoplasms. Ovarian hormone stimulation of these smoothmuscle tumors has been suggested, but the role of surgical or medical oophorectomy has not been established in patients with metastatic disease.
Cases: Two women with histologically confirmed uterine low-grade smooth-muscle tumors metastatic to the lung had progressive and complete tumor regression after oophorectomy and no further therapy.
Conclusion: Some uterine low-grade smooth-muscle tumors metastatic to the lung regress after oophorectomy. Removing ovarian hormone stimulation may result in complete tumor regression without the need for further therapy.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>9166348</pmid><doi>10.1016/S0029-7844(97)00033-1</doi><tpages>3</tpages></addata></record> |
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subjects | Adult Biological and medical sciences Diagnosis, Differential Disease-Free Survival Female Female genital diseases Follow-Up Studies Gynecology. Andrology. Obstetrics Humans Leiomyoma - diagnostic imaging Leiomyoma - surgery Leiomyosarcoma - diagnostic imaging Leiomyosarcoma - secondary Leiomyosarcoma - surgery Lung Neoplasms - diagnostic imaging Lung Neoplasms - secondary Lung Neoplasms - surgery Medical sciences Ovariectomy Radiography Remission Induction Tumors Uterine Neoplasms - pathology |
title | Regression of uterine low-grade smooth-muscle tumors metastatic to the lung after oophorectomy |
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