Regression of uterine low-grade smooth-muscle tumors metastatic to the lung after oophorectomy

Background: Metastatic uterine low-grade smooth-muscle tumors may present with pulmonary symptoms and radiographic lung abnormalities consistent with metastatic neoplasms. Ovarian hormone stimulation of these smoothmuscle tumors has been suggested, but the role of surgical or medical oophorectomy ha...

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Veröffentlicht in:Obstetrics and gynecology (New York. 1953) 1997-05, Vol.89 (5), p.850-852
Hauptverfasser: Abu-Rustum, Nadeem R., Curtin, John P., Burt, Michael, Jones, Walter B.
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container_issue 5
container_start_page 850
container_title Obstetrics and gynecology (New York. 1953)
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creator Abu-Rustum, Nadeem R.
Curtin, John P.
Burt, Michael
Jones, Walter B.
description Background: Metastatic uterine low-grade smooth-muscle tumors may present with pulmonary symptoms and radiographic lung abnormalities consistent with metastatic neoplasms. Ovarian hormone stimulation of these smoothmuscle tumors has been suggested, but the role of surgical or medical oophorectomy has not been established in patients with metastatic disease. Cases: Two women with histologically confirmed uterine low-grade smooth-muscle tumors metastatic to the lung had progressive and complete tumor regression after oophorectomy and no further therapy. Conclusion: Some uterine low-grade smooth-muscle tumors metastatic to the lung regress after oophorectomy. Removing ovarian hormone stimulation may result in complete tumor regression without the need for further therapy.
doi_str_mv 10.1016/S0029-7844(97)00033-1
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Ovarian hormone stimulation of these smoothmuscle tumors has been suggested, but the role of surgical or medical oophorectomy has not been established in patients with metastatic disease. Cases: Two women with histologically confirmed uterine low-grade smooth-muscle tumors metastatic to the lung had progressive and complete tumor regression after oophorectomy and no further therapy. Conclusion: Some uterine low-grade smooth-muscle tumors metastatic to the lung regress after oophorectomy. 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source MEDLINE; Journals@Ovid Complete
subjects Adult
Biological and medical sciences
Diagnosis, Differential
Disease-Free Survival
Female
Female genital diseases
Follow-Up Studies
Gynecology. Andrology. Obstetrics
Humans
Leiomyoma - diagnostic imaging
Leiomyoma - surgery
Leiomyosarcoma - diagnostic imaging
Leiomyosarcoma - secondary
Leiomyosarcoma - surgery
Lung Neoplasms - diagnostic imaging
Lung Neoplasms - secondary
Lung Neoplasms - surgery
Medical sciences
Ovariectomy
Radiography
Remission Induction
Tumors
Uterine Neoplasms - pathology
title Regression of uterine low-grade smooth-muscle tumors metastatic to the lung after oophorectomy
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