A probable conformational difference between recombinant and urinary erythropoietins
Urinary and recombinant human erythropoietin differ with respect to ease of iodination, inactivation by iodination, second derivative and circular dichroic spectra, rate of inactivation by trypsin and glycosylation pattern. All of these differences are compatible with a significant difference in con...
Gespeichert in:
Veröffentlicht in: | Proteins, structure, function, and bioinformatics structure, function, and bioinformatics, 1997-05, Vol.28 (1), p.94-98 |
---|---|
Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | Urinary and recombinant human erythropoietin differ with respect to ease of iodination, inactivation by iodination, second derivative and circular dichroic spectra, rate of inactivation by trypsin and glycosylation pattern. All of these differences are compatible with a significant difference in conformation of these two forms of erythropoietin. © 1997 Wiley‐Liss Inc. |
---|---|
ISSN: | 0887-3585 1097-0134 |
DOI: | 10.1002/(SICI)1097-0134(199705)28:1<94::AID-PROT9>3.0.CO;2-J |