Bacterial phospholipases and their role in virulence

Virulence of many bacterial pathogens is based, at least in part, on the action of phospholipases. The consequences may be immediate and direct, as in the action of Clostridium perfringens α toxin on red cells or platelets, or subtle, as with phosphatidylinositol-specific phospholipases of Listeria...

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Veröffentlicht in:	Trends in microbiology (Regular ed.) 1997-04, Vol.5 (4), p.156-161
1. Verfasser:	Songer, J. Glenn
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteria - pathogenicity Bacterial Infections - microbiology Bacterial Physiological Phenomena Bacterial Proteins - physiology Bacterial Toxins - metabolism Calcium-Binding Proteins Clostridium perfringens Clostridium perfringens - enzymology Clostridium perfringens - pathogenicity Corynebacterium pseudotuberculosis - enzymology Corynebacterium pseudotuberculosis - pathogenicity Humans Listeria monocytogenes Listeria monocytogenes - enzymology Listeria monocytogenes - pathogenicity Phosphatidylinositol Diacylglycerol-Lyase Phospholipases - physiology Pseudomonas aeruginosa - enzymology Pseudomonas aeruginosa - pathogenicity Type C Phospholipases - metabolism Virulence
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Beschreibung
Zusammenfassung:	Virulence of many bacterial pathogens is based, at least in part, on the action of phospholipases. The consequences may be immediate and direct, as in the action of Clostridium perfringens α toxin on red cells or platelets, or subtle, as with phosphatidylinositol-specific phospholipases of Listeria monocytogenes and other bacteria.
ISSN:	0966-842X 1878-4380
DOI:	10.1016/S0966-842X(97)01005-6