Cardiovascular hemodynamics in the swine following long-term placement of prosthetic grafts post right ventriculotomy

1. 1. Heart rate, cardiac output and arterial, pulmonary artery, central venous and pulmonary wedge pressures were measured in eight neutered male pigs of an average of 14 months of age and 145.0–231.0 kg body weight. 2. 2. These measurements were made 10–16 months after right ventriculotomy and placement of Gore-Tex® PTFE Vascular Grafts. 3. 3. Arithmetic means, standard deviations and coefficients of variation were calculated and the 95% confidence limits for ranges were established. 4. 4. Comparison of derived data with that from published data on swine and on humans indicated normal cardiovascular hemodynamics in this group. 5. 5. In addition, there was no gradient across the patched area. 6. 6. It appears, therefore, that these patches had no adverse effects on the cardiovascular system of growing pigs.