Copper and iron-induced oxidative damage in non-tumor bearing LEC rats

The copper and Iron status in the liver of non‐tumor bearing Long‐Evans Cinnamon (LEC) rats (average age 17 months) was investigated. A direct quantitation of loosely‐bound copper and iron was also investigated by using a chelating agent, nitrilotriacetic acid (NTA‐chelatable free copper and iron)....

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Veröffentlicht in:	Pathology international 1997-04, Vol.47 (4), p.203-208
Hauptverfasser:	Ma, Yuxiang, Zhang, Daxian, Kawabata, Teruyuki, Kiriu, Takahiro, Toyokuni, Shinya, Uchida, Koji, Okada, Shigeru
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals copper Copper - analysis Copper - metabolism DNA Damage Female Glutathione Transferase - biosynthesis Immunohistochemistry iron Iron - analysis Iron - metabolism LEC rat Lipid Peroxidation Liver - chemistry Liver - metabolism Liver - pathology Male oxidative damage Oxidative Stress Rats Rats, Inbred Strains Thiobarbituric Acid Reactive Substances
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