Ceftriaxone versus clavulanate-potentiated amoxycillin for prophylaxis against post-operative sepsis in biliary surgery: A prospective randomized study in 200 patients
Summary A prospective study was carried out in 200 consecutive patients undergoing biliary surgery to compare the prophylactic effectiveness of ceftriaxone and clavulanate-potentiated (CP-)amoxycillin. Patients were assigned in a randomized fashion to two groups and received ceftriaxone (2 g intrave...
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Veröffentlicht in: | Current medical research and opinion 1989, Vol.11 (6), p.354-359 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Summary
A prospective study was carried out in 200 consecutive patients undergoing biliary surgery to compare the prophylactic effectiveness of ceftriaxone and clavulanate-potentiated (CP-)amoxycillin. Patients were assigned in a randomized fashion to two groups and received ceftriaxone (2 g intravenously pre-operatively)or CP-amoxycillin (1200 mg, to be repeated for 2 more doses in the case of patients undergoing procedures other than elective cholecystectomy). Post-operative wound infection occurred in 4% of patients in each group. Administration of ceftriaxone was associated with a lower incidence of post-operative pyrexia and chest infection as well as with a shorter hospital stay. |
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ISSN: | 0300-7995 1473-4877 |
DOI: | 10.1185/03007998909110135 |