Effect of cannabinoids on spasticity and ataxia in multiple sclerosis

The chronic motor handicaps of a 30-year-old multiple sclerosis patient acutely improved while he smoked a marihuana cigarette. This effect was quantitatively assessed by means of clinical rating, electromyographic investigation of the leg flexor reflexes and electromagnetic recording of the hand ac...

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Veröffentlicht in:	Journal of neurology 1989-02, Vol.236 (2), p.120-122
Hauptverfasser:	MEINCK, H.-M, SCHONLE, P. W, CONRAD, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Ataxia - drug therapy Ataxia - etiology Biological and medical sciences Cannabinoids - therapeutic use Cannabis Humans Male Medical sciences Multiple Sclerosis - complications Multiple Sclerosis - drug therapy Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Muscle Spasticity - drug therapy Muscle Spasticity - etiology Neurology
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Zusammenfassung:	The chronic motor handicaps of a 30-year-old multiple sclerosis patient acutely improved while he smoked a marihuana cigarette. This effect was quantitatively assessed by means of clinical rating, electromyographic investigation of the leg flexor reflexes and electromagnetic recording of the hand action tremor. It is concluded that cannabinoids may have powerful beneficial effects on both spasticity and ataxia that warrant further evaluation.
ISSN:	0340-5354 1432-1459
DOI:	10.1007/BF00314410