Diagnostic criteria and clinical procedures in HIV-1 associated progressive multifocal leukoencephalopathy

The diagnosis of definite progressive multifocal leukoencephalopathy (PML) has been a neuropathological domain. We reviewed all Human Immunodeficiency Virus Type 1 (HIV-1) seropositive patients in our institution between 01.01.1989 and 31.12.1994 and identified 20 823 cases with PML by clinical and...

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Veröffentlicht in:	Journal of the neurological sciences 1997-03, Vol.147 (1), p.63-72
Hauptverfasser:	Giesen, H.J.v., Neuen-Jacob, E., Dörries, K., Jablonowski, H., Roick, H., Arendt, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS-Related Opportunistic Infections - blood AIDS-Related Opportunistic Infections - cerebrospinal fluid AIDS-Related Opportunistic Infections - diagnosis AIDS/HIV Biological and medical sciences Biopsy Clinical diagnosis Demography HIV-1 Human immunodeficiency virus Type-1 infection Human polyoma virus JC polymerase chain reaction Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Leukoencephalopathy, Progressive Multifocal - blood Leukoencephalopathy, Progressive Multifocal - cerebrospinal fluid Leukoencephalopathy, Progressive Multifocal - diagnosis Magnetic Resonance Imaging Male Medical sciences Middle Aged Neuropathology Progressive multifocal leukoencephalopathy Retrospective Studies Stereotactic brain biopsy Stereotaxic Techniques Tropical medicine
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Zusammenfassung:	The diagnosis of definite progressive multifocal leukoencephalopathy (PML) has been a neuropathological domain. We reviewed all Human Immunodeficiency Virus Type 1 (HIV-1) seropositive patients in our institution between 01.01.1989 and 31.12.1994 and identified 20 823 cases with PML by clinical and imaging criteria. Diagnosis was neuropathologically confirmed in 5 cases. Diagnostic criteria included rapid onset (
ISSN:	0022-510X 1878-5883
DOI:	10.1016/S0022-510X(96)05311-7