Soluble extracts from larval Ostertagia ostertagi modulating immune function

Soluble extracts from larval Ostertagia ostertagi modulating immune function

Soluble extracts from larval Ostertagia ostertagi modulating immune function. International Journal for Parasitology 19: 57–61. BALB/c mice were immunized with Ostertagia ostertagi antigens and keyhole limpet hemocyanin (KLH) or sheep erythrocytes (SR) for evaluation of antibody production by enzyme...

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Veröffentlicht in:International journal for parasitology 1989-02, Vol.19 (1), p.57-61
Hauptverfasser: Cross, D.A., Klesius, P.H.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
antibodies
Antibodies, Helminth - biosynthesis
antigens
Antigens, Helminth - immunology
calves
crossing
enzyme-linked immunosorbent assay
extracts
Holstein
immunization
immunomodulation
infection
Larva - immunology
larvae
lymphoblastogenesis
Mice
Mice, Inbred BALB C
Ostertagia - immunology
Ostertagia ostertagi
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Zusammenfassung:Soluble extracts from larval Ostertagia ostertagi modulating immune function. International Journal for Parasitology 19: 57–61. BALB/c mice were immunized with Ostertagia ostertagi antigens and keyhole limpet hemocyanin (KLH) or sheep erythrocytes (SR) for evaluation of antibody production by enzyme linked immunosorbent assay (ELISA) or modified Jerne plaque assay. One semi-purified larval antigen caused both decreased anti-KLH serum antibody levels and fewer anti-SR IgM-secreting B cells. This antigen was shown to depress lymphocyte blastogenesis to Concanavalin A when added to cultured BALB/c splenic lymphocytes.
ISSN:0020-7519
1879-0135
DOI:10.1016/0020-7519(89)90021-0