L-671, 329, A NEW ANTIFUNGAL AGENT: I. FERMENTATION AND ISOLATION

In screening for new antifungal agents from fungi, a new lipopeptide antifungal agent, L-671, 329, similar to echinocandin B, has been isolated from Zalerion arboricola. Studies indicate that L-671, 329 is produced under both solid and liquid fermentation conditions.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of antibiotics 1989/02/25, Vol.42(2), pp.163-167
Hauptverfasser:	SCHWARTZ, ROBERT E., GIACOBBE, ROBERT A., BLAND, JUDITH A., MONAGHAN, RICHARD L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents Antibiotics (antibacterial agents, antifungal agents) Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents antifungal agents Antifungal Agents - isolation & purification Antifungal Agents - pharmacology Applied microbiology Biological and medical sciences Candida albicans - drug effects Candida albicans - growth & development Chromatography, High Pressure Liquid Echinocandins Fermentation Fundamental and applied biological sciences. Psychology lipoproteins Microbiology peptide antibiotics Peptides Peptides, Cyclic - isolation & purification Peptides, Cyclic - pharmacology
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Beschreibung
Zusammenfassung:	In screening for new antifungal agents from fungi, a new lipopeptide antifungal agent, L-671, 329, similar to echinocandin B, has been isolated from Zalerion arboricola. Studies indicate that L-671, 329 is produced under both solid and liquid fermentation conditions.
ISSN:	0021-8820 1881-1469
DOI:	10.7164/antibiotics.42.163