Exploration and habituation in Purkinje cell degeneration mutant mice

Purkinje cell degeneration ( pcd) mutant mice lose virtually all Purkinje cells. It was found that the pcd mutants did not show within-sessions habituation in terms of hole-poking responses. This type of perseverative responding has been found in rats with limbic system damage and implies a role for...

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Veröffentlicht in:	Brain research 1989-02, Vol.479 (1), p.201-203
Hauptverfasser:	Lalonde, Robert, Manseau, Maryse, Botez, M.I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavioral psychophysiology Biological and medical sciences Cerebellum Cerebellum - physiology Exploratory Behavior - physiology Female Fundamental and applied biological sciences. Psychology Habituation, Psychophysiologic - physiology Habituation-hole poking Isolated neuron and nerve. Neuroglia Male Mice Mice, Neurologic Mutants - physiology Mouse pcd mutant Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Purkinje Cells - physiology Vertebrates: nervous system and sense organs
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Zusammenfassung:	Purkinje cell degeneration ( pcd) mutant mice lose virtually all Purkinje cells. It was found that the pcd mutants did not show within-sessions habituation in terms of hole-poking responses. This type of perseverative responding has been found in rats with limbic system damage and implies a role for the cerebellum in behavioral inhibition.
ISSN:	0006-8993 1872-6240
DOI:	10.1016/0006-8993(89)91354-1