Calcium Antagonists and Experimental Atherosclerosis

Conclusion The role of organic calcium antagonists in prevention of atherosclerosis in animals is unsettled and appears to involve interaction with variables not yet defined. Interpretation should therefore be made with caution and is premature at this time. Conclusions concerning the effectiveness...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 1989-03, Vol.190 (3), p.219-228
Hauptverfasser:	Kjeldsen, Knud, Stender, Steen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arteriosclerosis - physiopathology Arteriosclerosis - prevention & control Biological and medical sciences Blood Platelets - physiology Calcium - physiology Calcium Channel Blockers - therapeutic use Cardiovascular system Endothelium, Vascular - physiopathology flunarizine Humans Hyperlipidemias - physiopathology Medical sciences Miscellaneous Muscle, Smooth, Vascular - physiopathology nifedipine Pharmacology. Drug treatments reviews verapamil
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Beschreibung
Zusammenfassung:	Conclusion The role of organic calcium antagonists in prevention of atherosclerosis in animals is unsettled and appears to involve interaction with variables not yet defined. Interpretation should therefore be made with caution and is premature at this time. Conclusions concerning the effectiveness of calcium antagonists in suppressing atherosclerosis in humans must await the results of clinical trials with nifedipine and nicardipine (86).
ISSN:	0037-9727 1535-3702 1535-3699 1525-1373
DOI:	10.3181/00379727-190-42852a