Pluripotent hemopoietic stem cells are c-kit<low

Pluripotent hemopoietic stem cells (P-HSCs) were thought to be c-kit + , but recent reports indicate that they are c-kit low . In the present report, we provide evidence using Ly5 congenic mice that P-HSCs are c-kit

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Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1997-03, Vol.94 (6), p.2513-2517
Hauptverfasser:	Doi, H, Inaba, M, Yamamoto, Y, Taketani, S, Mori, S I, Sugihara, A, Ogata, H, Toki, J, Hisha, H, Inaba, K, Sogo, S, Adachi, M, Matsuda, T, Good, R A, Ikehara, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Sciences Bone Marrow Cells Hematopoietic Stem Cell Transplantation Hematopoietic Stem Cells - immunology Mice Mice, Inbred C57BL Polymerase Chain Reaction Proto-Oncogene Proteins c-kit - analysis Proto-Oncogene Proteins c-kit - biosynthesis Proto-Oncogene Proteins c-kit - genetics Spleen - cytology Thymus Gland - cytology
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Beschreibung
Zusammenfassung:	Pluripotent hemopoietic stem cells (P-HSCs) were thought to be c-kit + , but recent reports indicate that they are c-kit low . In the present report, we provide evidence using Ly5 congenic mice that P-HSCs are c-kit
ISSN:	0027-8424 1091-6490
DOI:	10.1073/pnas.94.6.2513