Production and Reversal of the Neuromuscular Pathology and Related Signs of Zinc Deficiency in Guinea Pigs

The purposes of this study were to use vocalization and posture as indices of the neuromuscular pathology that develops in zinc-deficient guinea pigs and to determine the rate of depletion before and of repletion after intraperitoneal (IP) zinc therapy. When severe signs of deficiency developed, tis...

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Veröffentlicht in:	The Journal of nutrition 1989-02, Vol.119 (2), p.196-201
Hauptverfasser:	O'Dell, Boyd L., Becker, James K., Emery, Michelle P., Browning, Jimmy D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences CARENCE MINERALE CINC COBAYE COBAYO DEFICIENCIA DE MINERALES deficiency signs Diet Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology guinea pig Guinea Pigs Injections, Intraperitoneal Male mobilizable zinc Motor Activity - physiology Neuromuscular Diseases - etiology Neuromuscular Diseases - therapy pathology remission SINTOMAS Skin Diseases - etiology SYMPTOME Tissue Distribution TRASTORNOS NEUROMUSCULARES TROUBLE NEUROMUSCULAIRE Vertebrates: anatomy and physiology, studies on body, several organs or systems Vocalization, Animal - physiology ZINC Zinc - administration & dosage Zinc - deficiency Zinc - metabolism zinc depletion
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Zusammenfassung:	The purposes of this study were to use vocalization and posture as indices of the neuromuscular pathology that develops in zinc-deficient guinea pigs and to determine the rate of depletion before and of repletion after intraperitoneal (IP) zinc therapy. When severe signs of deficiency developed, tissues were analyzed for their zinc content to assess sites of depletable and mobilizable zinc stores. Weanling guinea pigs were fed low (
ISSN:	0022-3166 1541-6100
DOI:	10.1093/jn/119.2.196