Hemorrhagic compression of the phrenic nerve after streptokinase infusion

A 72-year-old woman with acute myocardial infarction underwent intravenous streptokinase therapy following an unsuccessful attempt at right subclavian vein catheterization. Three hours after initiation of therapy, chest radiograph revealed a markedly elevated right hemidiaphragm. Subsequent computed...

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Veröffentlicht in:	The American journal of emergency medicine 1989-03, Vol.7 (2), p.185-186
Hauptverfasser:	Seaberg, David C., Generalovich, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences bleeding complications Catheterization, Central Venous - adverse effects Drug toxicity and drugs side effects treatment Female Hematoma - complications Hematoma - etiology Humans Infusions, Intravenous Medical sciences Miscellaneous (drug allergy, mutagens, teratogens...) Myocardial Infarction - therapy Nerve Compression Syndromes - etiology Pharmacology. Drug treatments Phrenic Nerve phrenic nerve paralysis Streptokinase Streptokinase - administration & dosage Streptokinase - adverse effects
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Zusammenfassung:	A 72-year-old woman with acute myocardial infarction underwent intravenous streptokinase therapy following an unsuccessful attempt at right subclavian vein catheterization. Three hours after initiation of therapy, chest radiograph revealed a markedly elevated right hemidiaphragm. Subsequent computed tomography and fluoroscopy of the chest revealed paralysis of the phrenic nerve by hematoma. This case demonstrates the hazards of attempted cannulation of noncompressible vessels when fibrinolytic therapy is anticipated.
ISSN:	0735-6757 1532-8171
DOI:	10.1016/0735-6757(89)90135-6