Use of stable isotopically labeled tracers for studies of metabolic kinetics: An overview

Stable isotopically labeled tracers offer a reliable and safe alternative to the use of radioactive tracers for studies of metabolic kinetics. This overview examines some of the principles and technical issues regarding mass spectrometry instrumentation, and reviews some of the approaches used in th...

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Veröffentlicht in:	Metabolism, clinical and experimental clinical and experimental, 1997-03, Vol.46 (3), p.322-329
1. Verfasser:	Patterson, Bruce W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Elements Functional investigation of endocrine glands and genital system Gas Chromatography-Mass Spectrometry - instrumentation Investigative techniques, diagnostic techniques (general aspects) Isotope Labeling Isotopes Kinetics Medical sciences Metabolism - physiology Models, Biological
Online-Zugang:	Volltext
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Zusammenfassung:	Stable isotopically labeled tracers offer a reliable and safe alternative to the use of radioactive tracers for studies of metabolic kinetics. This overview examines some of the principles and technical issues regarding mass spectrometry instrumentation, and reviews some of the approaches used in the application of stable isotopically labeled tracers to studies of protein, lipid, and carbohydrate metabolic kinetics.
ISSN:	0026-0495 1532-8600
DOI:	10.1016/S0026-0495(97)90260-2