A typical case of pemphigoid gestationis with a unique pattern of intercellular immunofluorescence

Summary Pemphigoid gestationis is an autoimmune bullous disorder affecting pregnant women which typically presents in the second and third trimester of pregnancy with an itchy bullous eruption on the abdomen and limbs. The diagnosis is confirmed by the presence of complement‐binding IgG antibasement...

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Veröffentlicht in:British journal of dermatology (1951) 1997-02, Vol.136 (2), p.245-248
Hauptverfasser: JONES, S.A.VAUGHAN, BHOGAL, B.S., BLACK, M.M., CLEMENT, M., HASHIMOTO, T., NISHIKAWA, T.
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Sprache:eng
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Zusammenfassung:Summary Pemphigoid gestationis is an autoimmune bullous disorder affecting pregnant women which typically presents in the second and third trimester of pregnancy with an itchy bullous eruption on the abdomen and limbs. The diagnosis is confirmed by the presence of complement‐binding IgG antibasement membrane zone (BMZ) antibodies, which bind to the roof of salt‐split skin. We describe a case of clinically typical pemphigoid gestationis with the combination of intercellular IgG and BMZ IgG and C3 staining on immunofluorescence, a pattern which is unique for this condition.
ISSN:0007-0963
1365-2133
DOI:10.1046/j.1365-2133.1997.d01-1179.x