The conformation and activity relationship of benzofuran derivatives as angiotensin II receptor antagonists

We have synthesized various benzofuran derivatives to study the relationship between the conformation and the angiotensin II type I receptor antagonistic activity. We have synthesized various benzofuran derivatives and studied the relationship between the conformation and the angiotensin II receptor...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bioorganic & medicinal chemistry 1997-02, Vol.5 (2), p.445-459
Hauptverfasser:	Yoo, Sung-eun, Lee, Seung-Heui, Kim, Soo-Kyung, Lee, Sung-Hou
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin Receptor Antagonists Benzofurans - chemistry Benzofurans - pharmacology Magnetic Resonance Spectroscopy Molecular Structure
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	We have synthesized various benzofuran derivatives to study the relationship between the conformation and the angiotensin II type I receptor antagonistic activity. We have synthesized various benzofuran derivatives and studied the relationship between the conformation and the angiotensin II receptor and antagonistic activity.
ISSN:	0968-0896 1464-3391
DOI:	10.1016/S0968-0896(96)00244-1