Systemic Sclerosis Associated with Diabetes Insipidus

A rare case of systemic sclerosis that preceded the development of diabetes insipidus is reported. This 25-year-old man presented with Raynaud's phenomenon and ulceration of the tip of the right thumb. The diagnosis of systemic sclerosis was based on findings of proximal scleroderma, sclerodact...

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Veröffentlicht in:Internal Medicine 1997, Vol.36(1), pp.73-76
Hauptverfasser: HARADA, Masaru, YOSHIDA, Hiroshi, MIMURA, Yoshihiro, OHTSUBO, Korenori, KAWAGUCHI, Takumi, MURASHIMA, Shiro, SASATOMI, Kurumi, KOMAI, Ayako, MIYAZATO, Minoru, IWAO, Tadashi, SATA, Michio, TANIKAWA, Kyuichi
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Sprache:eng
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Zusammenfassung:A rare case of systemic sclerosis that preceded the development of diabetes insipidus is reported. This 25-year-old man presented with Raynaud's phenomenon and ulceration of the tip of the right thumb. The diagnosis of systemic sclerosis was based on findings of proximal scleroderma, sclerodactyly, serological abnormalities, and skin abnormalities verified histologically. Partial central diabetes insipidus was later diagnosed after the sudden appearance of polyuria and polydipsia. Coexistence of systemic sclerosis with diabetes insipidus suggests that diabetes insipidus in this patient might have occurred via an autoimmune mechanism. (Internal Medicine 36: 73-76, 1997)
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.36.73