Cationic liposome-mediated transfection

Cationic liposome-mediated transfection

A lipid named DOTMA has been created that forms unilamellar liposomes which complex with DNA and RNA for the transfection of mammalian cells, including suspension cells and hybridomas.

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Bibliographische Detailangaben
Veröffentlicht in:Nature (London) 1989-01, Vol.337 (6205), p.387-388
Hauptverfasser: Felgner, P. L, Ringold, G. M
Format: Artikel
Sprache:eng
Schlagworte:
Cellular biology
Deoxyribonucleic acid
DNA
DNA - genetics
Liposomes
Mammals
Proteins
Quaternary Ammonium Compounds
RNA - genetics
Transfection
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Beschreibung
Zusammenfassung:A lipid named DOTMA has been created that forms unilamellar liposomes which complex with DNA and RNA for the transfection of mammalian cells, including suspension cells and hybridomas.
ISSN:0028-0836
1476-4687
DOI:10.1038/337387a0