Chronic eosinophilic leukaemia (CEL): a distinct myeloproliferative disease

Chronic eosinophilic leukaemia has not yet been clearly defined, mainly due to the fact that it has not been conclusively shown as a monoclonal disease which should be separated from chronic myelogenous leukaemia, acute myelogenous leukaemia with eosinophilia (AML, FAB M4Eo), and the idiopathic hype...

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Veröffentlicht in:	British journal of haematology 1997-01, Vol.96 (1), p.117-123
Hauptverfasser:	Weide, Rudolf, Rieder, Harald, Mehraein, Yasemien, Wolf, Martin, Kaiser, Ulrich, Seifart, Ulf, Görg, Christian, Havemann, Klaus
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blast Crisis Chromosomes, Human, Pair 15 Chronic Disease chronic eosinophilic leukaemia Fatal Outcome Hematologic and hematopoietic diseases Humans Hypereosinophilic Syndrome - blood Hypereosinophilic Syndrome - diagnosis Hypereosinophilic Syndrome - genetics In Situ Hybridization, Fluorescence Karyotyping Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Leukocyte Count Male Medical sciences Middle Aged monoclonal myeloproliferative disease Platelet Count Trisomy
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Zusammenfassung:	Chronic eosinophilic leukaemia has not yet been clearly defined, mainly due to the fact that it has not been conclusively shown as a monoclonal disease which should be separated from chronic myelogenous leukaemia, acute myelogenous leukaemia with eosinophilia (AML, FAB M4Eo), and the idiopathic hypereosinophilic syndrome. We report a patient with a white blood cell count of 17.6 × 109/l with 74% eosinophils, normal platelet count and haemoglobin. No blasts were seen in the peripheral blood and the percentage of blasts in the bone marrow was
ISSN:	0007-1048 1365-2141
DOI:	10.1046/j.1365-2141.1997.d01-1991.x