Does endogenous sex hormone binding globulin influence the contraceptive effect of levonorgestrel?

On the basis of four previous clinical studies a direct relationship of the contraceptive effect of levonorgestrel (expressed as a suppression of ovarian function) to individual levels of sex hormone binding globulin may be assumed. The rationale of this dependence seems to be the protection against...

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Veröffentlicht in:	Steroids 1988-10, Vol.52 (4), p.399-400
1. Verfasser:	Cekan, S.Z.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Contraceptive Agents, Female Female Humans Levonorgestrel Norgestrel - pharmacology Sex Hormone-Binding Globulin - physiology
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	On the basis of four previous clinical studies a direct relationship of the contraceptive effect of levonorgestrel (expressed as a suppression of ovarian function) to individual levels of sex hormone binding globulin may be assumed. The rationale of this dependence seems to be the protection against metabolic degradation which is provided by sex hormone globulin to levonorgestrel.
ISSN:	0039-128X 1878-5867
DOI:	10.1016/0039-128X(88)90166-3