Cystic fibrosis DNA markers in Alabama blacks

Cystic fibrosis DNA markers in Alabama blacks

DNA samples from unrelated Alabama blacks with no family history of cystic fibrosis (CF) were analyzed with DNA markers linked to cf. Allelic frequencies of genetic markers detected by probes p metH, p metD, XV2c, KM19, and pJ3.11 were compared to those of other populations. Allelic frequencies for...

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Veröffentlicht in:Genomics (San Diego, Calif.) Calif.), 1988-11, Vol.3 (4), p.385-388
Hauptverfasser: Martin, Rodger K., Kaplan, Gail C., Hodge, Thomas W., Barker, Peter E.
Format: Artikel
Sprache:eng
Schlagworte:
Alabama
Alleles
Black or African American
Black People - genetics
Cystic Fibrosis - genetics
DNA - blood
DNA - genetics
Gene Frequency
Genetic Markers
Genotype
Humans
Lymphocytes - analysis
Nigeria
White People - genetics
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Zusammenfassung:DNA samples from unrelated Alabama blacks with no family history of cystic fibrosis (CF) were analyzed with DNA markers linked to cf. Allelic frequencies of genetic markers detected by probes p metH, p metD, XV2c, KM19, and pJ3.11 were compared to those of other populations. Allelic frequencies for pJ3.11, XV2c, and KM19 in Alabama blacks and previously studied Caucasian populations were similar. In contrast, the met locus allelic frequencies in Alabama blacks were markedly different from those in Caucasian populations.
ISSN:0888-7543
1089-8646
DOI:10.1016/0888-7543(88)90132-2