Magnetic resonance imaging in Pelizaeus-Merzbacher disease

Cranial computed tomography of a boy with clinical characteristics of the classic form of Pelizaeus-Merzbacher disease did not reveal a notable abnormality other than enlarged ventricles. Magnetic resonance imaging, however, demonstrated diffuse changes in the white matter with sparing of scattered...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Pediatric neurology 1988-03, Vol.4 (2), p.124-125
Hauptverfasser:	Shimomura, Chieko, Matsui, Akira, Choh, Hiroyuki, Funahashi, Masuko, Suzuki, Yasuyuki, Tsuchiya, Kazuhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Brain - pathology Cerebellum - pathology Cerebral Cortex - pathology Cerebral Ventricles - pathology Diffuse Cerebral Sclerosis of Schilder - diagnosis Humans Magnetic Resonance Imaging Male Myelin Sheath - pathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Cranial computed tomography of a boy with clinical characteristics of the classic form of Pelizaeus-Merzbacher disease did not reveal a notable abnormality other than enlarged ventricles. Magnetic resonance imaging, however, demonstrated diffuse changes in the white matter with sparing of scattered small areas, suggesting persistent myelin islands which are a typical neuropathologic finding in Pelizaeus-Merzbacher disease. Magnetic resonance imaging appears more useful than computed tomography in confirming the diagnosis of Pelizaeus-Merzbacher disease.
ISSN:	0887-8994 1873-5150
DOI:	10.1016/0887-8994(88)90055-0