Sterols of Acanthamoeba culbertsoni strain A-1

Two new sterols, stigmasta-5,7,22,25-tetraene-3 β -ol ( 1 ) and stigmasta-5,7,14,22,25-pentaene-3 β -ol ( 2 ), have been characterized along with ergosterol and 7-dehydrostigmasterol in the nonsaponifiable fraction of the total lipids extracted from trophozoites of Acanthamoeba culbertsoni strain A-...

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Veröffentlicht in:Steroids 1988-05, Vol.51 (5), p.551-558
Hauptverfasser: Mehdi, Haider, Garg, H.S., Garg, N.K., Bhakuni, D.S.
Format: Artikel
Sprache:eng
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Zusammenfassung:Two new sterols, stigmasta-5,7,22,25-tetraene-3 β -ol ( 1 ) and stigmasta-5,7,14,22,25-pentaene-3 β -ol ( 2 ), have been characterized along with ergosterol and 7-dehydrostigmasterol in the nonsaponifiable fraction of the total lipids extracted from trophozoites of Acanthamoeba culbertsoni strain A-1 (virulent strain). However, these sterols were found to be absent in the nonpathogenic strain C-7 of A. culbertsoni .
ISSN:0039-128X
1878-5867
DOI:10.1016/0039-128X(88)90051-7