THYROID FUNCTION IN MALE ZUCKER RATS EXPOSED TO COLD

THYROID FUNCTION IN MALE ZUCKER RATS EXPOSED TO COLD

Non-obese and obese Zucker rats were exposed to 6 °C for 20 days. At the end of the experiment thyroid stimulating hormone (TSH), circulating thyroid hormones, and the weights of the thyroid gland and a brown adipose tissue pad were measured. TSH and 3,5,3'-triiodothyronine concentrations and...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Experimental physiology 1988-11, Vol.73 (6), p.1029-1031
Hauptverfasser: Whitaker, E. M., Robinson, A. C., Rayfield, K. M., Hervey, G. R.
Format: Artikel
Sprache:eng
Schlagworte:
Adipose Tissue, Brown - pathology
Animals
Biological and medical sciences
Body Temperature Regulation
Cold Temperature - adverse effects
Male
Medical sciences
Metabolic diseases
Obesity
Obesity - blood
Obesity - pathology
Obesity - physiopathology
Rats
Rats, Zucker
Thyroid Gland - physiopathology
Thyroid Hormones - blood
Thyrotropin - blood
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Non-obese and obese Zucker rats were exposed to 6 °C for 20 days. At the end of the experiment thyroid stimulating hormone (TSH), circulating thyroid hormones, and the weights of the thyroid gland and a brown adipose tissue pad were measured. TSH and 3,5,3'-triiodothyronine concentrations and brown adipose tissue weights increased in response to cold in both phenotypes but by larger amounts in obese rats. Free thyroxine was lower in obese rats. There appears to be no defect in thyroid function in congenitally obese rats exposed to cold, or in their ability to develop brown adipose tissue.
ISSN:0958-0670
0144-8757
1469-445X
DOI:10.1113/expphysiol.1988.sp003216