An inexpensive spacer for use with metered-dose bronchodilators in young asthmatic children

A 1‐liter soft drink plastic bottle was modified as a spacer for use with a metereddose bronchodilator. Its efficacy was tested on 22 children aged 3.9–7.5 years who had acute asthma. They were randomly selected to receive aerosolized salbutamol or placebo via the plastic bottle. Children who receiv...

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Veröffentlicht in:	Pediatric pulmonology 1988, Vol.5 (4), p.244-246
Hauptverfasser:	Teo, Joseph, Kwang, Lee Woon, Yip, William C. L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Albuterol - administration & dosage Albuterol - therapeutic use Asthma - drug therapy Biological and medical sciences Child Child, Preschool Clinical Trials as Topic Double-Blind Method double-blind study General pharmacology heart rate Humans Medical sciences Methods Nebulizers and Vaporizers Peak Expiratory Flow Rate Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments placebo Random Allocation Salbutamol aerosol Salbutamol aerosol placebo double‐blind study peak expiratory flow rate heart rate
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Beschreibung
Zusammenfassung:	A 1‐liter soft drink plastic bottle was modified as a spacer for use with a metereddose bronchodilator. Its efficacy was tested on 22 children aged 3.9–7.5 years who had acute asthma. They were randomly selected to receive aerosolized salbutamol or placebo via the plastic bottle. Children who received the salbutamol showed significantly greater degree of bronchodilation than those who received the placebo. No significant adverse effects were observed. Cylindrical plastic bottles of 1‐liter capacity may thus be used as a convenient and cheap spacer to effectively deliver metered‐dose bronchodilators to children during acute asthma.
ISSN:	8755-6863 1099-0496
DOI:	10.1002/ppul.1950050411