Coexistence of choline acetyltransferase and nerve growth factor receptors in the rat basal forebrain

Coexistence of choline acetyltransferase and nerve growth factor receptors in the rat basal forebrain

Choline acetyltransferase (ChAT) and nerve growth factor (NGF) receptors have previously been shown to be expressed in magnocellular forebrain neurones in the rat. We have now examined their colocalization in these neurones. Using monoclonal antibodies raised against ChAT and NGF receptors we demons...

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Veröffentlicht in:Neuroscience letters 1988-11, Vol.94 (1), p.138-144
Hauptverfasser: Dawbarn, D., Allen, S.J., Semenenko, F.M.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Basal forebrain
Brain - enzymology
Brain - metabolism
Choline acetyltransferase
Choline O-Acetyltransferase - analysis
Immunocytochemistry
Immunoenzyme Techniques
Nerve growth factor receptor
Nerve Growth Factors - metabolism
Neurons - metabolism
Rats
Rats, Inbred Strains
Receptors, Cell Surface - analysis
Receptors, Nerve Growth Factor
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Zusammenfassung:Choline acetyltransferase (ChAT) and nerve growth factor (NGF) receptors have previously been shown to be expressed in magnocellular forebrain neurones in the rat. We have now examined their colocalization in these neurones. Using monoclonal antibodies raised against ChAT and NGF receptors we demonstrate here a high degree of colocalization.
ISSN:0304-3940
1872-7972
DOI:10.1016/0304-3940(88)90284-4