New steroidal saponin from Hosta sieboldiana

An extract of the edible parts of Hosta sieboldiana suppressed the growth of P388 mouse leukemic cells. A new steroidal saponin was isolated from Hosta sieboldiana in this study, and the structure was determined by a spectroscopic analysis to be (25R)-3β-(α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranosyl...

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Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2010, Vol.74 (4), p.861-864
Hauptverfasser:	Yada, H., National Food Research Inst., Tsukuba, Ibaraki (Japan), Kimura, T, Suzuki, M, Ohnishi Kameyama, M, Shinmoto, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences CHEMICAL STRUCTURE ESPECTROMETRIA ESTRUCTURA QUIMICA EXTRACTOS EXTRACTS EXTRAIT FREE RADICALS Fundamental and applied biological sciences. Psychology HOSTA Hosta sieboldiana http://www.fao.org/aos/agrovoc#c_15893 http://www.fao.org/aos/agrovoc#c_2767 http://www.fao.org/aos/agrovoc#c_33488 http://www.fao.org/aos/agrovoc#c_3672 http://www.fao.org/aos/agrovoc#c_4297 http://www.fao.org/aos/agrovoc#c_4795 http://www.fao.org/aos/agrovoc#c_6795 http://www.fao.org/aos/agrovoc#c_7283 LEUCEMIA LEUCEMIE LEUKAEMIA MICE new steroidal saponin RADICAL LIBRE RADICALES LIBRES RATON SAPONINAS SAPONINE SAPONINS Saponins - chemistry SOURIS SPECTROMETRIE SPECTROMETRY spirostan-2,3-diol Spirostans - analysis STRUCTURE CHIMIQUE
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Zusammenfassung:	An extract of the edible parts of Hosta sieboldiana suppressed the growth of P388 mouse leukemic cells. A new steroidal saponin was isolated from Hosta sieboldiana in this study, and the structure was determined by a spectroscopic analysis to be (25R)-3β-(α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranosyl-(1→3)-[β-D-glucopyranosyl-(1→2)]-β-D-glucopyranosyl-(1→4)-β-D-galactopyranosyl)-5α-spirostan-2α-ol.
ISSN:	0916-8451 1347-6947
DOI:	10.1271/bbb.90807