Proto-oncogene expression in germ cell development

Proto-oncogene expression in germ cell development

Some proto-oncogenes thought to be involved in the development of the neoplastic phenotype in various somatic cells are expressed during gametogenesis in testes and ovaries. Studies of their expression in germ cells may lead to the elucidation of their function and give insight into the molecular as...

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Veröffentlicht in:Trends in genetics 1988-07, Vol.4 (7), p.183-187
Hauptverfasser: Propst, Friedrich, Rosenberg, Michael P., Vande Woude, George F.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Gene Expression Regulation
Humans
Male
Mice
Oogenesis
Proto-Oncogenes
Rats
Spermatogenesis
Transcription, Genetic
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Zusammenfassung:Some proto-oncogenes thought to be involved in the development of the neoplastic phenotype in various somatic cells are expressed during gametogenesis in testes and ovaries. Studies of their expression in germ cells may lead to the elucidation of their function and give insight into the molecular aspects of germ cell differentiation.
ISSN:0168-9525
DOI:10.1016/0168-9525(88)90073-X